In a luxurious seaside villa, a modest young woman finds herself in the company of a strange family: an unknown and wealthy father, his extravagant wife, his daughter, an ambitious woman, a rebellious teenager, and their creepy maid. Someone is lying. Between suspicions and lies, a mystery grows and the evil spreads.

　　来自南太平洋萨摩亚群岛的体育记者杜克（约翰尼·德普 Johnny Depp 饰）和他的律师朋友刚佐博士（本尼西奥·德·托尔 Benicio Del Tore 饰）一起开车前往拉斯维加斯，寻找他们的“美国梦”。一路上，他们带了大量毒品和酒精，也遇到形形色色的人，药物作用下，许多迷乱和癫狂的画面出现，让他们分不清幻觉和现实，到底哪个更残破，哪个更肮脏扭曲。两个人的混沌，加上拉斯维加斯本身的纸醉金迷，“美国梦”似乎遥不可及，两个人留下垃圾场一样的五星级酒店房间，无法停止迷幻的路途……

　　Jimmy Reardon and Mary Spalding head their respective organizations, Mary as Director of the Organized Crime Unit, Jimmy the boss of his family's organized crime business. Unexpectedly, Mary successfully recruits Jimmy to act as her star individual in the OCU's underground intelligence network on organized crime. However, it's a two-way street as she needs to provide Jimmy with inside information on police knowledge of his businesses. Both Mary and Jimmy need to tread lightly in their relationship while they try and maintain a grip hold on their respective businesses.

　　维达和亚瑟来自于两个完全不懂的生活背景，感性动人， 有时候古怪忧伤，却始终真诚如一。　　全新演绎一段夹在两个矛盾冲突的家庭之间的现代茱莉亚和罗密欧故事。

结束了墨西哥的假期，正值青春年少的梅尔（佩顿·里斯特 Peyton List 饰）和茱尔丝（卡梅隆·古德曼 Cameron Goodman 饰）乘夜晚的航班回到洛杉矶。适值深夜，大雨瓢泼，贪图便宜的两个女孩和刚刚认识的青年塞斯（詹姆斯·辛德 James Snyder 饰）、马特（戴夫·鲍尔 Dave Power 饰）搭上一辆深色的机场巴士。除梅尔等人之外，还有一个中年人与他们同行。