改编自直木奖作家朝井まかて的同名小说。在江户，年轻时被称为马喰町的“猪、鹿、蝶”的以乃、志花、阿蝶三人各有烦恼，突然决定扔下工作和家庭，启程去伊势神宫参拜。这种抛却一切到伊势参拜的旅行在当时十分流行。

　　宙斯一直享有众神之王的地位。直到一天早上醒来，他发现额头上有一条皱纹。神经症开始发作，让他走上了一条危险、偏执的道路。宙斯确信自己的陨落即将来临，并开始在各处看到这一迹象。　　宙斯曾经可靠的兄弟，冥界之神哈迪斯，正在秘密地放开对黑暗世界的控制。大量死者等待处理，他们变得焦躁不安。天后赫拉（珍妮·麦克蒂尔饰）以她独特的方式统治着地球以及宙斯。但她的权力和自由受到宙斯日益增长的偏执的威胁，被迫采取行动。宙斯叛逆的儿子狄俄尼索斯（纳巴汉·里兹旺饰）则失去了控制，即将与他的父亲发生彗星撞地球般的冲突。　　在地球上，人们渴望改变，然而大海、风暴、地震（以及战马）之神波塞冬（克利夫·柯蒂斯饰）更关心他的超级游艇的大小以及下一场聚会的地点。他对凡人的福祉不感兴趣。不幸的是，对于众神来说，一些凡人已经开始意识到这一点······　　里迪（奥罗拉·佩里诺饰）、俄耳甫斯（基连·斯科特饰）、卡诺伊斯（米夏·巴特勒饰）和阿里（蕾拉·法扎德饰）这几个凡人来自不同的行业，并且在对抗宙斯的战斗中命运相连。每个人都扮演着截然不同的角色，他们中的任何一个都可能是命中注定的弑神者。

一次偶然中，室内设计师拉萨（黛薇卡?霍内 Davika Hoorne 饰）遇见了富家花花公子帕卡彭（林柏光 Dome Pakorn Lam 饰），帕卡彭轻浮的行为举止令拉萨十分不齿，之后，拉萨又在工作中同帕卡彭重逢，随着时间的推移，两人虽然表面上吵吵闹闹，但心的距离却越来越近。 　　然而，就在拉萨觉得自己和帕卡彭打得火热之时，帕卡彭竟然提出了分手，没过多久，便传出了帕卡彭热烈追求总理之女的消息。得知此事的拉萨大受打击，然而她人微言轻，对此无可奈何只能接受。在帕卡彭的内心里依然深爱着拉萨，只是，他有一个不得不完成的任务，有一个不能不报的仇，知道真相的拉萨想要阻止冲动的帕卡彭，然而一切早已经来不及了。

　　George Tracy and Charlie Sorel, both thirty-six years of age, are writers - a Paris novelist and Hollywood screenwriter, respectively - best friends, and partners in crime in skirt chasing. Charlie is shot dead aboard a yacht during a party by filmmaker Sir Leopold Sartori after he catches Charlie fooling around with his wife, Rusty, Charlie's body which falls overboard and which is not found. Sartori's act is despite he being a notorious womanizer himself. Charlie's sparsely attended funeral service, at which George provides the eulogy, demonstrates how Charlie's womanizing ways negatively affected his so called friendships. Staying at Charlie's Malibu beach house, George meets a beautiful young woman who seems to be suffering from amnesia, but is drawn to Charlie's house. George initially believes she is one of Charlie's conquests, but she eventually comes to the realization and is able to convince George that she is Charlie reincarnated. George ultimately believes it is God's divine retribution for Charlie to come back as an object of his own derision. But together and individually, George and Charlie have to devise a way for Charlie to live in this new female body, George who has no money to support Charlie, and Charlie's estate which is bankrupt. In addition, Charlie, who has always been a player, figures that she should be able to capitalize on her new womanhood, which includes using knowledge of her former indiscretions as a man, and getting back at Sir Leo. But she may also be able to eke out a lucrative life as she becomes the object of affection of wealthy momma's boy, Bruce Minton III.

　　故事发生在不同于现实的异世界中。在这个世界中，所有的人类均拥有被称为守护精灵的动物同伴，这些动物是人类灵魂的具象体现。女主角莱拉·贝拉奎亚成长于英国牛津的约旦学院。在她前往伦敦寻找失踪的朋友罗杰的过程中，莱拉发现一系列儿童失踪事件与神秘物质尘埃有所关联。随着故事展开，她还发现了涉及到阿斯瑞尔勋爵和玛莉莎·库尔特的危险秘密。